Manganese is an essential trace mineral that serves as a cofactor for several important enzymes involved in energy metabolism, bone formation, and antioxidant defense. Research suggests that manganese plays a critical role in activating manganese superoxide dismase, one of the body's primary enzymes for protecting cells against oxidative stress. Studies indicate that adequate manganese intake supports healthy bone development and may contribute to normal blood sugar regulation through its involvement in glucose metabolism and insulin secretion. Additionally, research has linked manganese to the production of collagen and other compounds important for wound healing. Commonly available as manganese gluconate, manganese sulfate, and manganese bisglycinate, this mineral is found naturally in whole grains, nuts, leafy vegetables, and tea, though individual needs can vary based on diet and overall health status.
Compare this supplementResearch suggests that manganese plays a meaningful role in bone health, with review-level evidence indicating it pro...
View studies →Research suggests that manganese plays a meaningful role in antioxidant defense, primarily through its function as a ...
View studies →The six studies provided do not contain research relevant to manganese and blood sugar regulation. The linked sources...
View studies →Research suggests that manganese plays a role in metabolic processes at the cellular and molecular level, with studie...
View studies →Research suggests that manganese plays a meaningful supporting role in wound healing through several distinct mechani...
View studies →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Capsule | 5–10 mg | Daily | wound healing and connective tissue support | Studied in combination formulations for collagen synthesis and wound repair in clinical settings |
| Tablet | 15–30 mg | Daily | blood sugar regulation and metabolic support | Used in research on manganese supplementation and glycemic control; upper tolerable intake level set at 11 mg/day by IOM |
| Tablet | 5–15 mg | Daily | bone health and antioxidant support | Common in clinical trials studying manganese in combination with calcium and other minerals for bone density |
| Tablet | 1.8–2.3 mg | Daily | general health and meeting adequate intake levels | Based on established Adequate Intake (AI) levels from Institute of Medicine; commonly used in multivitamin/mineral trials |