Vitamin E is a group of fat-soluble compounds — including tocopherols and tocotrienols — that serve as important antioxidants in the body, helping protect cells from oxidative damage caused by free radicals. Research suggests that vitamin E plays a supportive role in immune function, and studies have explored its potential benefits for skin health, wound healing, cognitive function, and eye health, though findings vary in strength depending on the specific outcome studied. Among its forms, d-alpha-tocopherol is the most biologically active, while mixed tocopherols and tocotrienols have drawn growing interest for their complementary properties. Found naturally in nuts, seeds, vegetable oils, and leafy greens, vitamin E remains one of the more widely studied nutrients in antioxidant and aging-related research.
Compare this supplementResearch suggests that vitamin E may play a meaningful role in supporting skin health, particularly through its antio...
View studies →Research suggests that vitamin E's role in supporting cognitive function remains uncertain and largely unproven, with...
View studies →Research suggests that vitamin E may play a role in supporting eye health, particularly in relation to age-related ma...
View studies →Research suggests that vitamin E plays a meaningful role in supporting immune function, with a 1988 review reporting ...
View studies →Research suggests that vitamin E's role in wound healing is promising in certain contexts but remains inconsistent ac...
View studies →Research suggests that vitamin E exerts meaningful antioxidant activity across a range of biological contexts, with a...
View studies →Nattokinase has strong fibrinolytic activity and vitamin E has mild antiplatelet effects; combine...
View details →Both have mild anticoagulant effects that may be additive.
View details →Both have mild anticoagulant properties that may be additive.
View details →Both have antiplatelet effects that may be additive.
View details →Both have mild blood-thinning effects that may add up.
View details →Selenium and vitamin E work together as complementary antioxidants.
View details →Vitamin C regenerates oxidized vitamin E, creating a synergistic antioxidant network.
View details →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Capsule | 400 IU | Daily | Antioxidant support and general health | Common dose in numerous clinical trials for antioxidant effects |
| Capsule | 800–1,000 IU | Daily | Cognitive function and Alzheimer's disease progression | Used in RCTs including the DATATOP study and Alzheimer's disease trials |
| Capsule | 400–800 IU | Daily | Eye health, including age-related macular degeneration (AREDS formulation) | Based on AREDS and AREDS2 clinical trials |
| Capsule | 15 mg | Daily | General health maintenance matching recommended dietary allowance | Based on NIH recommended dietary allowance (RDA) for adults (15 mg = ~22.5 IU natural form) |
| Capsule | 200–400 IU | Daily | Immune function and cardiovascular antioxidant support | Commonly used range in immune function and cardiovascular RCTs |
| Topical | 5–20 mg | As needed | Skin health and wound healing | Typical concentration range used in topical formulations studied in dermatology trials |