Pine bark extract, most widely studied under the branded form Pycnogenol derived from French maritime pine (Pinus pinaster), is rich in proanthocyanidins and other polyphenolic compounds with notable antioxidant activity. Research suggests it may support cardiovascular health by promoting healthy blood circulation and assisting with blood pressure regulation, while studies indicate potential benefits for cognitive function, particularly in areas of attention and memory. Clinical investigations have also explored its role in supporting skin elasticity and hydration, eye health related to retinal microcirculation, and respiratory function in individuals with mild asthma. Although findings across these areas are promising, much of the research involves relatively small study populations, and the strength of evidence varies depending on the specific health outcome being examined.
Compare this supplementResearch suggests that Pycnogenol (pine bark extract) possesses meaningful antioxidant activity, with laboratory and ...
View studies →Research suggests that pine bark extract (Pycnogenol) may offer some benefit as an adjunct to standard asthma therapy...
View studies →Research suggests that Pine Bark Extract (Pycnogenol) may support blood circulation through several mechanisms, inclu...
View studies →Research suggests that Pycnogenol may support cognitive function, attention, memory, and mood in healthy middle-aged ...
View studies →Research suggests that Pine Bark Extract (Pycnogenol) may offer benefits for eye health, though the evidence base rem...
View studies →Research suggests that Pine Bark Extract (Pycnogenol) may offer several skin health benefits, with a 2016 review of c...
View studies →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Extract | 1–2 mg | Daily | Asthma support in children (per kg body weight) | Pediatric clinical trials using weight-based dosing for respiratory outcomes |
| Extract | 120–150 mg | Daily | Blood circulation and chronic venous insufficiency | Common in RCTs on venous tone and edema reduction |
| Extract | 100–150 mg | Daily | Blood pressure regulation and general antioxidant support | Common in clinical trials on hypertension and oxidative stress |
| Extract | 150–200 mg | Daily | Cognitive function and memory support | Based on RCTs examining attention and working memory in adults |
| Extract | 40–100 mg | Three times daily | Eye health and diabetic retinopathy | Based on clinical trials examining retinal blood flow and visual acuity |
| Extract | 75–150 mg | Daily | Skin health, photoprotection, and hydration | Common in RCTs on UV-induced skin damage and skin elasticity |