Research suggests that the evidence for wormwood as an appetite stimulant is limited and mixed across the available studies. A randomized controlled trial found that rinsing with wormwood tea appeared to reduce the brain's motivational response to high-calorie food cues in healthy women, though the researchers noted this does not confirm any actual change in eating behavior. A rat study testing an extract of Artemisia absinthium found no significant appetite-stimulating effect at any dose tested, directly challenging its traditional reputation as an orexigenic agent. A comparative analysis of traditional bitter tonics supports the theoretical basis for wormwood's digestive and appetite-related uses — noting that bitter compounds may stimulate gastric secretion via the vagus nerve — but this mechanistic rationale has yet to be confirmed by robust human clinical trials, leaving the overall evidence inconclusive.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Disgust evoked by strong wormwood bitterness influences the processing of vis... | RCT | 2017 | — | 72 |
| Bitterness values for traditional tonic plants of southern Africa. | Other | 2013 | Supports | 67 |
| The effect of hydro-alcoholic extract of Artemisia absinthium on appetite in ... | Other | 2015 | — | 62 |