Research suggests that vitamin D plays a recurring role in nutrient absorption contexts, appearing across studies examining conditions and interventions that disrupt or impair the gut's ability to absorb micronutrients. Studies indicate that vitamin D deficiency is commonly observed alongside other micronutrient shortfalls in populations with compromised intestinal function, including people with celiac disease following a gluten-free diet, individuals with obesity, and those who have undergone bariatric surgery such as biliopancreatic diversion — with supporting evidence drawn from reviews, observational studies, and long-term surgical outcome data. A 2020 narrative review of studies in children and adolescents found that inulin, a type of dietary fiber, was associated with improved absorption of vitamins D and E, and that fructans more broadly may support a gut environment conducive to better nutrient uptake, suggesting that the gut microbiome may be a relevant factor in how well vitamin D is absorbed. However, the overall body of evidence reviewed here is largely indirect, with vitamin D appearing as one of several deficient nutrients rather than as the primary focus of absorption research, and the studies are predominantly reviews and observational in design, which limits the ability to draw firm causal conclusions about vitamin D's specific role in nutrient absorption independent of broader dietary and gut health factors.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Nutritional Imbalances in Adult Celiac Patients Following a Gluten-Free Diet. | Review | 2021 | Mixed | 100 |
| Nutrition: Micronutrients. | Review | 2024 | Neutral | 95 |
| Micronutrient-deficient diets and possible environmental enteric dysfunction ... | Other | 2024 | Neutral | 90 |
| Nutrient absorption. | Other | 2000 | Neutral | 90 |
| Nutritional analysis of commercially available, complete plant- and meat-base... | Other | 2024 | Neutral | 85 |
| Demographic variation and socioeconomic inequalities associated with the trip... | Other | 2024 | Neutral | 85 |
| Biliopancreatic diversion. | Other | 1998 | Supports | 85 |
| Structural and biochemical analysis of a B12 super-binder | Other | 2024 | Neutral | 80 |
| Overnutrition is a risk factor for iron deficiency in children and young peop... | Other | 2024 | Neutral | 80 |
| Malnutrition in patients with obesity: An overview perspective. | Review | 2024 | Supports | 80 |
| Interspecies interactions drive bacterial proteome reorganisation and emergen... | Other | 2025 | Neutral | 75 |
| Participation in a voluntary alcohol abstinence program (Alcohol Free for 40)... | Other | 2022 | Neutral | 75 |
| Changes in nutrient absorption in children and adolescents caused by fructans... | Review | 2020 | Supports | 75 |
| Cross-talks between osteoporosis and gut microbiome. | Review | 2025 | Supports | 70 |
| Reliance on self-reports and estimated food composition data in nutrition res... | Other | 2023 | Neutral | 70 |
| Genome-wide association study reveals loci with sex-specific effects on plasm... | Other | 2022 | Neutral | 70 |
| Macrophage-augmented organoids recapitulate the complex pathophysiology of vi... | Other | 2025 | Neutral | 65 |
| Drosophila Undigested Metabolite Profiling reveals age related loss of intest... | Other | 2023 | Neutral | 65 |
| Nutrient and mineral retention and vitamin D absorption in low-birth-weight i... | RCT | 1983 | — | 65 |
| Impact of commercial gut health interventions on caecal metagenome and broile... | Other | 2024 | Neutral | 60 |
| Real world evidence of calcifediol use and mortality rate of COVID-19 hospita... | Other | 2021 | Neutral | 60 |
| Bariatric surgery and vitamin D: key messages for surgeons and clinicians bef... | Review | 2016 | Mixed | 60 |
| ASD mutations in the ciliary gene <i>CEP41</i> impact development of projecti... | Other | 2025 | Neutral | 55 |
| Dual-modulation of nutrient-transporter axis and functionalized carriers: A p... | Review | 2025 | Supports | 55 |
| Mismatch: A comparative study of vitamin D status in British-Bangladeshi migr... | Other | 2020 | Neutral | 55 |
| An RNA regulates iron homeostasis and host mucus colonization in <i>Bacteroid... | Other | 2025 | Neutral | 50 |
| The Prevalence of Iron and Vitamin D Deficiencies in Pediatric Patients With ... | Other | 2023 | Neutral | 50 |
| Could nutrition modulate COVID-19 susceptibility and severity of disease? A s... | Other | 2020 | Supports | 50 |
| DiatOmicBase, a gene-centered platform to mine functional omics data across d... | Other | 2024 | Neutral | 45 |
| Elevated Blood Glucose Levels as a Primary Risk Factor for the Severity of CO... | Other | 2021 | Neutral | 45 |
| Using stable isotope tracers to study bone metabolism in children. | Review | 2019 | Neutral | 45 |
| Computational metabolic modeling unveils gut microbiome’s role in metabolic s... | Other | 2024 | Neutral | 40 |
| Pectin Modulates Calcium Absorption in Polarized Caco-2 Cells via a Pathway D... | Other | 2023 | Supports | 40 |
| Identification of transporters essential for survival of <i>Leishmania</i> ... | Other | 2025 | Neutral | 35 |
| An in-line digestive cartridge increases enteral fat and vitamin absorption i... | Other | 2022 | Supports | 35 |
| A genome-wide CRISPR screen reveals how diatoms thrive in dynamic light | Other | 2025 | Neutral | 30 |
| Postoperative Osteoporosis in Subjects with Morbid Obesity Undergoing Bariatr... | Review | 2023 | Mixed | 30 |
| Developmental factors drive the compartmentalised and discontinuous maturatio... | Other | 2025 | Neutral | 25 |
| Nanoplasmonic SERS reveals previously uncharacterised indole derivative in <... | Other | 2025 | Neutral | 20 |
| Quantifying the varying harvest of fermentation products from the human gut m... | Other | 2024 | Neutral | 15 |