Vitamin B5 (Pantothenic Acid)

Vitamins

Vitamin B5, also known as pantothenic acid, is a water-soluble B vitamin that plays a central role in energy metabolism by serving as a precursor to coenzyme A, which is essential for synthesizing and breaking down fatty acids, carbohydrates, and proteins. Research suggests that pantethine, a derivative form of B5, may support healthy cholesterol levels by influencing lipid metabolism, while dexpanthenol has been studied for its potential benefits in wound healing and skin hydration. Studies also indicate that adequate pantothenic acid intake contributes to the normal production of adrenal hormones and may play a supportive role in maintaining hormonal balance during periods of stress. Because it is widely found in foods ranging from eggs and legumes to whole grains, deficiency is uncommon, though interest in supplemental forms continues to grow in the research community.

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What the research says

Common dosages

These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.

Form Dose range Frequency Studied for Source
Capsule 500–1,000 mg Daily Acne and skin health Based on RCTs including Leung et al. studies on pantothenic acid for acne reduction
Capsule 1,000–2,000 mg Daily Acne vulgaris reduction in higher-dose intervention studies Higher dose range used in Leung 1995 pilot study on pantothenic acid and acne
Capsule 5–10 mg Daily General metabolism support and hormonal balance Common supplemental dose near RDA; RDA is 5 mg/day for adults per Institute of Medicine
Tablet 300–600 mg Daily Cholesterol management and lipid profile improvement Used in clinical trials examining pantethine (active form) effects on LDL and triglycerides
Topical 2–5 mg As needed Wound healing and skin barrier repair (as dexpanthenol/provitamin B5) Common in clinical wound care studies using dexpanthenol creams at 2–5% concentration

Common supplement forms

Calcium pantothenate Pantethine Dexpanthenol
Medical Disclaimer: Noyemi provides information from published research for educational purposes only. This content is not medical advice and does not replace consultation with a qualified healthcare provider. Always consult your doctor before starting, stopping, or changing any supplement regimen, especially if you take medications or have existing health conditions.