Vitamin B5, also known as pantothenic acid, is a water-soluble B vitamin that plays a central role in energy metabolism by serving as a precursor to coenzyme A, which is essential for synthesizing and breaking down fatty acids, carbohydrates, and proteins. Research suggests that pantethine, a derivative form of B5, may support healthy cholesterol levels by influencing lipid metabolism, while dexpanthenol has been studied for its potential benefits in wound healing and skin hydration. Studies also indicate that adequate pantothenic acid intake contributes to the normal production of adrenal hormones and may play a supportive role in maintaining hormonal balance during periods of stress. Because it is widely found in foods ranging from eggs and legumes to whole grains, deficiency is uncommon, though interest in supplemental forms continues to grow in the research community.
Compare this supplementResearch suggests that the available published evidence linking vitamin B5 (pantothenic acid) specifically to hormona...
View studies →Research suggests that Vitamin B5 (pantothenic acid) plays a foundational role in cellular energy metabolism, primari...
View studies →Research suggests a potential link between pantothenic acid levels and cholesterol management, particularly regarding...
View studies →The single study provided does not investigate Vitamin B5 (Pantothenic Acid) or skin health in any capacity; it inste...
View studies →Research on Vitamin B5 (pantothenic acid) and wound healing does not appear to be directly supported by the single st...
View studies →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Capsule | 500–1,000 mg | Daily | Acne and skin health | Based on RCTs including Leung et al. studies on pantothenic acid for acne reduction |
| Capsule | 1,000–2,000 mg | Daily | Acne vulgaris reduction in higher-dose intervention studies | Higher dose range used in Leung 1995 pilot study on pantothenic acid and acne |
| Capsule | 5–10 mg | Daily | General metabolism support and hormonal balance | Common supplemental dose near RDA; RDA is 5 mg/day for adults per Institute of Medicine |
| Tablet | 300–600 mg | Daily | Cholesterol management and lipid profile improvement | Used in clinical trials examining pantethine (active form) effects on LDL and triglycerides |
| Topical | 2–5 mg | As needed | Wound healing and skin barrier repair (as dexpanthenol/provitamin B5) | Common in clinical wound care studies using dexpanthenol creams at 2–5% concentration |