Research suggests that Tribulus terrestris may support sexual function and libido in both men and women, with the bulk of available evidence coming from randomized controlled trials and reviews that generally point in a positive direction. Studies indicate improvements in desire, arousal, and satisfaction across several populations, including men with mild to moderate erectile dysfunction, premenopausal women with low sexual desire, and postmenopausal women, as measured by validated questionnaires like the IIEF and FSFI. However, the picture is not entirely clear: at least one placebo-controlled trial in men found no significant benefit over placebo at the dose and duration tested, and a 2016 review cautioned that the widely repeated claim that Tribulus terrestris works by raising testosterone levels is not well supported by current evidence, with some researchers proposing a nitric oxide-based mechanism instead. Additional limitations across the body of evidence include small sample sizes, short study durations, variable dosing and extract standardization, and the use of multi-ingredient formulas in some trials, all of which make it difficult to draw firm conclusions about the herb's effects in isolation.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Evaluation of the efficacy and safety of Tribulus terrestris in male sexual d... | RCT | 2017 | Supports | 72 |
| Pro-sexual and androgen enhancing effects of Tribulus terrestris L.: Fact or ... | Review | 2016 | Mixed | 67 |
| Tribulus terrestris and female reproductive system health: A comprehensive re... | Review | 2021 | Supports | 62 |
| Puncture vine (Tribulus Terrestris L.) in control of health and reproduction. | Review | 2021 | Supports | 57 |
| Tribulus terrestris for treatment of sexual dysfunction in women: randomized ... | RCT | 2014 | Supports | 52 |
| Efficacy of Tribulus Terrestris for the treatment of premenopausal women with... | RCT | 2018 | Supports | 47 |
| Efficacy of Tribulus terrestris for the treatment of hypoactive sexual desire... | RCT | 2016 | Supports | 42 |
| Effect of a multi-ingredient based food supplement on sexual function in wome... | Other | 2019 | Supports | 37 |
| Recent studies on aphrodisiac herbs for the management of male sexual dysfunc... | Review | 2011 | Supports | 32 |
| Sexual asthenia: Tradamixina versus Tadalafil 5 mg daily. | RCT | 2012 | Supports | 27 |
| Effects of herbal preparation on libido and semen quality in boars. | RCT | 2011 | Supports | 22 |
| Tribulus terrestris versus placebo in the treatment of erectile dysfunction: ... | RCT | 2014 | — | 17 |