Tongkat Ali (Longjack) for Libido And Sexual Function

Strong evidence 14 studies

Research suggests that Tongkat Ali (Eurycoma longifolia) may support libido, erectile function, and testosterone levels in men, with the evidence base spanning animal studies, small randomized controlled trials, and several systematic reviews and meta-analyses that generally point in a positive direction. Studies indicate that the herb may work through multiple mechanisms, including testosterone modulation, stress hormone reduction, and — based on laboratory findings — inhibition of enzymes involved in erectile function such as PDE-5 and ROCK-II, though these mechanistic findings have yet to be fully translated into robust clinical evidence. A 2015 meta-analysis pooling data from only two eligible trials found that improvements in erectile function scores did not reach statistical significance overall, though a subgroup analysis hinted at potential benefit in men with lower baseline function, and a 2022 systematic review found a statistically significant testosterone-raising effect in hypogonadal men specifically. Across the literature, limitations are consistent and notable: sample sizes are generally small, study durations are short, methodological quality varies, and a 2019 analysis of popular ED supplements found that the broader evidence base for such ingredients — including tongkat ali — remains thin when scrutinized carefully, meaning confident clinical conclusions cannot yet be drawn.

Related studies

Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.

Title Type Year Direction Match
Eurycoma longifolia Jack enhances libido in sexually experienced male rats. Other 1997 Supports 98
Phytoandrogenic properties of Eurycoma longifolia as natural alternative to t... Review 2014 Supports 90
A 6-month, double-blind, placebo-controlled, randomized trial to evaluate the... RCT 2021 Supports 88
Efficacy of Tongkat Ali (Eurycoma longifolia) on erectile function improvemen... Meta-analysis 2015 Supports 85
Effect of Tongkat Ali on stress hormones and psychological mood state in mode... Other 2013 Supports 85
Asian herbals and aphrodisiacs used for managing ED. Review 2017 Supports 80
Review on a Traditional Herbal Medicine, Eurycoma longifolia Jack (Tongkat Al... Review 2016 Supports 78
Phosphodiesterase-5 Inhibitory Activity of Canthin-6-One Alkaloids and the Ro... Other 2022 Supports 75
Rho-Kinase II Inhibitory Potential of Eurycoma longifolia New Isolate for the... Other 2019 Supports 73
Eurycoma longifolia (Jack) Improves Serum Total Testosterone in Men: A System... Systematic review 2022 Supports 72
Do "testosterone boosters" really increase serum total testosterone? A system... Systematic review 2024 Supports 68
A Multifaceted Review of Eurycoma longifolia Nutraceutical Bioactives: Produc... Review 2023 Supports 65
An Analysis of Popular Online Erectile Dysfunction Supplements. Systematic review 2019 Neutral 65
Tongkat Ali (Eurycoma longifolia Jack): a review on its ethnobotany and pharm... Review 2010 Supports 62

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Medical Disclaimer: Noyemi provides information from published research for educational purposes only. This content is not medical advice and does not replace consultation with a qualified healthcare provider. Always consult your doctor before starting, stopping, or changing any supplement regimen, especially if you take medications or have existing health conditions.