Research suggests that Tongkat Ali may support energy-related outcomes by promoting more consolidated wakefulness during active periods and reducing physiological markers of stress such as cortisol, which is often associated with fatigue. A small randomized controlled study in moderately stressed adults found improvements in self-reported mood states including tension and confusion alongside reductions in cortisol, while an animal study observed that supplementation helped organize sleep-wake cycles in ways that may support daytime alertness. The available human evidence is limited in scope, consisting of a small short-term trial and a published protocol for a larger trial in perimenopausal women whose results have not yet been reported, meaning conclusions about energy and fatigue benefits remain preliminary. Overall, the existing evidence leans in a supportive direction but is insufficient to draw firm conclusions, and findings from more robust human trials are needed before strong claims can be made.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Eurycoma longifolia (Tongkat Ali) supplementation enhances sleep and wake con... | Other | 2024 | Supports | 72 |
| Effect of Tongkat Ali on stress hormones and psychological mood state in mode... | Other | 2013 | Supports | 67 |
| Effects of Eurycoma longifolia Jack standardised water extract (Physta) on we... | RCT | 2023 | Neutral | 62 |