Research suggests that sweet potatoes contain a range of bioactive compounds — including anthocyanins, polyphenols, carotenoids, flavonoids, and storage proteins like sporamin — that demonstrate antioxidant and free-radical-scavenging properties across multiple lines of investigation. The available evidence comes primarily from in vitro laboratory studies, animal experiments, and narrative reviews rather than human clinical trials, with one mouse study suggesting antioxidant enzyme activity may be enhanced by sweet potato extract supplementation. Studies indicate that antioxidant potency varies considerably depending on the variety of sweet potato (purple-fleshed varieties have been most extensively studied), the specific compound being measured, and how the food is processed or cooked — for instance, steaming sweet potato leaves appears to preserve or even enhance antioxidant activity, while boiling causes substantial losses. Overall, while the preclinical evidence consistently points in a supportive direction, the relative scarcity of well-designed human trials and the known challenges around bioavailability of compounds like anthocyanins mean that the practical significance of these effects in living people remains to be more firmly established.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Tuber storage proteins. | Review | 2003 | Supports | 72 |
| Preparation and antioxidant activity of phosphorylated polysaccharide from pu... | Other | 2021 | Supports | 67 |
| Characterization, antioxidant and antitumor activities of polysaccharides fro... | Other | 2015 | Supports | 62 |
| Antioxidant and prebiotic activity of five peonidin-based anthocyanins extrac... | Other | 2018 | Supports | 57 |
| Harnessing the health benefits of purple and yellow-fleshed sweet potatoes: P... | Review | 2024 | Supports | 52 |
| Effect of infrared drying with multifrequency ultrasound pretreatments on the... | Other | 2019 | Supports | 47 |
| Conventional, ultrasound-assisted, and accelerated-solvent extractions of ant... | Other | 2016 | Supports | 42 |
| Delaying the harvest induces bioactive compounds and maintains the quality of... | Other | 2020 | Supports | 37 |
| Effects of domestic cooking methods on polyphenols and antioxidant activity o... | Other | 2014 | Supports | 32 |
| Anthocyanins From Sweet Potatoes (Ipomoea batatas): Bioavailability, Mechanis... | Review | 2025 | Supports | 27 |
| Natural Deep Eutectic Solvent-Based Microwave-Assisted Extraction of Total Fl... | Other | 2022 | Supports | 22 |
| Immunomodulatory and Antioxidant Effects of Purple Sweet Potato Extract in LP... | Other | 2015 | Supports | 17 |