Spirulina for Blood Pressure Regulation

Research suggests that spirulina may support blood pressure regulation by improving the ability of blood vessels to relax and increasing the availability of nitric oxide, a molecule central to vascular function. The available evidence on this specific mechanism comes from a single 2025 preclinical study using an enzyme-treated spirulina extract applied to arterial tissue from aged rats, which found reduced oxidative stress markers and enhanced vasodilation responses in both large and small arteries. Studies indicate that the small resistance arteries most directly involved in blood pressure control showed particularly notable effects, though it is important to acknowledge that laboratory findings in animal tissue do not necessarily translate to the same outcomes in living humans. The current body of research on this topic is extremely limited, and well-designed human clinical trials, such as randomized controlled trials, would be needed before drawing firm conclusions about spirulina's role in blood pressure regulation.