Serrapeptase is a proteolytic enzyme originally isolated from bacteria found in the intestines of silkworms, where it helps dissolve cocoon fibers. Though often grouped with amino acid-based compounds, it functions as an enzyme that breaks down proteins involved in inflammation and tissue repair. Research suggests serrapeptase may help reduce swelling, thin mucus secretions, and support recovery from minor injuries or surgical procedures, with several clinical studies exploring its potential for easing sinus congestion, sore throat discomfort, and postoperative inflammation. Studies indicate that enteric-coated formulations are commonly used to protect the enzyme from stomach acid, allowing it to reach the small intestine for absorption. While findings are promising in areas like pain and inflammation management, researchers note that larger, well-designed trials are still needed to fully establish its effectiveness across different applications.
Compare this supplementThese are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Tablet | 10–30 mg | Three times daily | Anti-inflammatory and pain relief | Common range used in clinical trials for post-operative inflammation and pain |
| Tablet | 5–10 mg | Twice daily | Cough relief and mucus reduction | Studied in trials for sputum viscosity reduction and chronic airway conditions |
| Tablet | 10 mg | Three times daily | Sinus and congestion relief | Dose used in RCTs for chronic sinusitis and upper respiratory tract symptoms |
| Tablet | 10–60 mg | Daily | Wound healing and post-surgical swelling | Range observed across multiple clinical studies on edema and tissue repair |