Pqq (Pyrroloquinoline Quinone) for Sleep Quality

Research suggests that PQQ supplementation may be associated with improvements in sleep quality, based on findings summarized in a 2024 narrative review of double-blind, placebo-controlled trials. The review also noted benefits across several other domains, including cognitive function and mood, painting a broader picture of PQQ as a potentially multifunctional compound. However, the evidence base for sleep specifically is limited — the available summary rests on a single review article rather than independently reported trial data, and narrative reviews carry inherent limitations including selective reporting and lack of statistical pooling. Overall, while the direction of the research is promising, stronger and more targeted evidence from well-designed clinical trials would be needed to draw firm conclusions about PQQ's effects on sleep quality.