Research suggests that PQQ may support anti-aging processes primarily through its role in promoting mitochondrial biogenesis and functioning as an antioxidant, mechanisms that are distinct from but potentially complementary to other compounds studied in the longevity space. The available evidence on PQQ for anti-aging comes from a single 2026 review article, which is among the more preliminary forms of scientific literature, and the review itself characterized the broader evidence base as limited. Studies indicate that while the theoretical rationale for PQQ's anti-aging properties is grounded in plausible biological pathways, robust confirmation through rigorous clinical trials remains lacking. Readers should weigh these findings with the understanding that a single review article represents an early stage of evidence, and stronger conclusions will require well-designed human studies.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Comparison of anti-aging effect of PQQ (Pyrroloquinoline quinone) and NMN/NR ... | Review | 2026 | Mixed | 100 |