Licorice root, derived from the Glycyrrhiza glabra plant, has been used in traditional medicine systems worldwide for centuries and continues to attract modern scientific interest. Research suggests it may support digestive comfort, with studies indicating that DGL (deglycyrrhizinated licorice) in particular shows promise for easing acid reflux and heartburn symptoms by helping to protect the stomach lining. Beyond digestive health, preliminary research has explored licorice root's potential benefits for soothing sore throats, supporting kidney function, and addressing certain skin conditions, with its bioactive compounds demonstrating anti-inflammatory and antioxidant properties in laboratory settings. While these findings are encouraging, much of the research remains early-stage, and licorice root — especially in its whole form containing glycyrrhizin — may interact with certain medications, making informed conversations with a healthcare provider worthwhile.
Compare this supplementThe available research on licorice root for digestive health is limited in what can be summarized here, as the one id...
View studies →Research suggests that the available studies linked here do not directly investigate licorice root and kidney health ...
View studies →Research on licorice root specifically for sore throat relief is extremely limited in the available evidence base, wi...
View studies →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Capsule | 500–1,000 mg | Daily | General digestive support and anti-inflammatory use | Common in clinical trials; typical standardized root powder capsule dosing |
| Extract | 75–150 mg | Twice daily | Acid reflux and heartburn (deglycyrrhizinated licorice, DGL form) | Common in clinical trials for GERD and dyspepsia using DGL extracts |
| Extract | 400–800 mg | Three times daily | Digestive health and gastric mucosal protection | Based on RCTs using standardized licorice root extract for functional dyspepsia |
| Extract | 100–300 mg | Daily | Kidney health and oxidative stress reduction | Based on limited clinical studies examining nephroprotective effects of glycyrrhizin-standardized extracts |
| Liquid | 2–4 g | Three times daily | Sore throat relief and upper respiratory support | Traditional and herbal medicine use; referenced in European Medicines Agency (EMA) monographs |
| Topical | 1–2 mg | Twice daily | Skin health, hyperpigmentation, and anti-inflammatory skin conditions | Based on clinical studies using topical licorice gel or cream with glabridin content |