Ganoderma (Reishi Tcm) for Liver Health

Research suggests that Ganoderma lucidum extract may support liver health by reducing liver enzyme levels and improving antioxidant markers in healthy adults. The available evidence comes from a single randomized, double-blind, placebo-controlled crossover trial of 42 healthy volunteers, which reported decreases in GOT and GPT liver enzymes alongside improvements in plasma antioxidant capacity, glutathione levels, and reduced oxidative damage; the study also noted that some participants with mild fatty liver showed apparent normalization on ultrasound imaging. While the direction of this trial is promising, the evidence base is limited to one relatively small study conducted in healthy volunteers, meaning findings may not generalize to individuals with existing liver conditions, and broader conclusions await replication in larger and more diverse populations.