Feverfew (Tanacetum parthenium) is a flowering plant in the daisy family that has been used in traditional herbalism for centuries, particularly for fevers and headaches. Research suggests that its active compound, parthenolide, may help modulate inflammatory pathways and inhibit the release of certain chemicals involved in migraine onset, such as serotonin and prostaglandins. Several clinical studies indicate that regular use of feverfew leaf extract may reduce the frequency and severity of migraines over time, though findings have been mixed and more rigorous trials are still needed. Commonly available as standardized leaf extracts, feverfew continues to attract scientific interest as a complementary approach to headache and migraine management, and anyone considering it may find it worthwhile to explore the current literature and consult a healthcare provider.
Compare this supplementResearch suggests that feverfew and its primary active compound parthenolide demonstrate meaningful anti-inflammatory...
View studies →Research suggests that feverfew may offer some benefit for migraine relief, though the evidence base remains limited ...
View studies →Research suggests that feverfew has been examined primarily in the context of migraine prevention rather than fever m...
View studies →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Capsule | 100–300 mg | Daily | Anti-inflammatory and fever management | Traditional use and observational studies; higher range used in some anti-inflammatory research |
| Capsule | 50–100 mg | Daily | Migraine prevention | Common in clinical trials for migraine prophylaxis using dried leaf preparations |
| Capsule | 2.08–18.75 mg | Three times daily | Migraine prevention | Based on RCTs using CO2 extract standardized to parthenolide content |
| Extract | 6.25–18.75 mg | Three times daily | Headache and migraine relief | Based on RCTs using MIG-99 standardized feverfew extract |
| Tablet | 82 mg | Daily | Migraine prevention | Dose used in key RCTs including Murphy et al. and Johnson et al. |