Sangre De Grado (Dragon's Blood)

Herbal Supplements

Sangre de Grado, commonly known as Dragon's Blood, is a deep red sap harvested from the Croton lechleri tree native to the Amazon basin, where it has a long history of traditional use for wound care and digestive complaints. Research suggests that the sap contains a rich profile of proanthocyanidins and the alkaloid taspine, which may contribute to its studied anti-inflammatory and antimicrobial properties. Studies indicate that one of its key compounds, crofelemer, has shown promise in supporting gut health and managing certain types of diarrhea by modulating chloride ion secretion in the intestinal lining. Preliminary research also points to potential benefits in wound healing, with some evidence suggesting the sap may help promote tissue repair and protect against infection, though further clinical studies are needed to fully understand its effects.

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What the research says

Common dosages

These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.

Form Dose range Frequency Studied for Source
Extract 100–500 mg Daily Anti-inflammatory, antimicrobial support Range observed across preclinical and early-phase human studies
Extract 125–250 mg Four times daily HIV-associated diarrhea, secretory diarrhea Used in Phase II/III clinical trials with crofelemer extract
Liquid 500 mg Four times daily Diarrhea management, traveler's diarrhea Based on clinical trials using standardized SP-303 (Provir/Crofelemer) derived from Sangre de Grado
Liquid 5–10 ml Twice daily Gut health, gastrointestinal inflammation Traditional and ethnobotanical use; diluted resin taken orally
Topical As needed Wound healing, skin inflammation, insect bites Traditional use; applied directly as latex resin to affected area

Common supplement forms

Croton lechleri sap
Medical Disclaimer: Noyemi provides information from published research for educational purposes only. This content is not medical advice and does not replace consultation with a qualified healthcare provider. Always consult your doctor before starting, stopping, or changing any supplement regimen, especially if you take medications or have existing health conditions.