Licorice root has a long history in traditional medicine for soothing digestive discomfort, and the deglycyrrhizinated (DGL) form has been specifically processed to remove glycyrrhizin, a compound associated with potential side effects like elevated blood pressure. Research suggests that DGL may help support the stomach's protective mucosal lining, which is why it has been studied in the context of acid reflux, heartburn, and general digestive wellness. Studies indicate that DGL chewable tablets, taken before meals, may promote a more comfortable digestive experience by encouraging the body's natural defense mechanisms in the gut. While the evidence is promising, particularly for mild gastrointestinal concerns, findings vary across studies, and anyone with ongoing digestive issues may benefit from discussing options with a healthcare provider.
Compare this supplementThe studies linked here do not contain research on licorice root or DGL for digestive health, and instead cover unrel...
View studies →The studies provided do not contain research relevant to Licorice Root (DGL) or gut health — all three focus on COVID...
View studies →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Capsule | 400–800 mg | Three times daily | Digestive health and gut lining support | Common range in clinical and traditional use protocols |
| Extract | 300–600 mg | Daily | Gut health and anti-inflammatory digestive support | Based on standardized DGL extract studies and product formulations |
| Powder | 1–2 g | Three times daily | General digestive health and mucosal integrity | Traditional use and herbal medicine guidelines |
| Tablet | 380 mg | Three times daily | Acid reflux and heartburn relief | Common in clinical trials using chewable DGL tablets before meals |
| Tablet | 760 mg | Twice daily | Peptic ulcer and gastric mucosal support | Used in RCTs evaluating DGL for ulcer management |