Clove and clove oil have a long history in traditional medicine, particularly for dental discomfort, and modern research has begun to explore the science behind these uses. The primary active compound, eugenol, has been widely studied for its anti-inflammatory, antimicrobial, and antioxidant properties, and studies indicate it may help support oral health by reducing bacterial growth and soothing minor gum irritation. Research also suggests that clove extracts may offer digestive benefits, potentially easing discomfort associated with bloating and nausea. Available as whole cloves, ground spice, or concentrated clove oil, this familiar kitchen staple continues to attract scientific interest, though more large-scale human studies are needed to fully understand its range of effects and long-term safety profile.
Compare this supplementResearch suggests that clove and clove oil, particularly through their primary active compound eugenol, demonstrate m...
View studies →Research suggests that clove oil demonstrates meaningful antimicrobial and antifungal activity across a broad range o...
View studies →Research on clove and clove oil for antioxidant support in humans is not well represented in the currently linked evi...
View studies →Research on clove and clove oil specifically for digestive health is not well represented in the studies linked here....
View studies →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Extract | 250–500 mg | Daily | Antioxidant support and anti-inflammatory effects | Based on human and in vitro studies examining clove extract standardized to eugenol |
| Extract | 500–1,000 mg | Daily | Blood glucose regulation and metabolic support | Used in small-scale RCTs examining clove extract effects on fasting blood glucose |
| Oil | 1–5 mg | As needed | Dental and oral health, topical application for toothache and gum pain | Common in clinical and dental research; eugenol-based formulations studied in oral health trials |
| Oil | 0.5–1 ml | As needed | Topical antimicrobial and anti-inflammatory application | Referenced in clinical studies on clove oil diluted in carrier oil for topical use |
| Powder | 1–3 g | Daily | Digestive health and antimicrobial properties | Traditional use corroborated by clinical observations; used in herbal formulations |