Chaste tree berry, derived from the plant Vitex agnus-castus, has a long history of traditional use for women's reproductive health and has been the subject of growing scientific interest. Research suggests that this herb may influence hormonal balance by acting on the pituitary gland, particularly in relation to prolactin levels, which play a role in menstrual cycle regulation. Studies indicate that chaste tree berry may help ease common premenstrual symptoms such as breast tenderness, mood changes, and irritability, with several clinical trials showing meaningful improvements compared to placebo. It has also been explored as a supportive option for menstrual irregularities and fertility-related concerns, though researchers note that more large-scale studies are needed to fully understand its mechanisms and long-term effects.
Compare this supplementResearch suggests that Vitex agnus-castus (chaste tree berry) may help reduce symptoms associated with premenstrual s...
View studies →Research suggests that chaste tree berry and related Vitex species may influence reproductive hormone levels, with th...
View studies →Research suggests that plants in the Vitex family — which includes chaste tree berry (Vitex agnus-castus) and related...
View studies →Research suggests that chaste tree berry shows promise as a remedy for PMS relief, with a 2000 review of herbal remed...
View studies →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Capsule | 400–500 mg | Daily | Hormonal balance and luteal phase support | Common in clinical trials using dried fruit/berry preparations |
| Extract | 4 mg | Daily | PMS and premenstrual dysphoric disorder (PMDD) | Based on RCTs using BNO 1095 standardized extract |
| Extract | 20–40 mg | Daily | PMS relief and menstrual cycle regulation | Common in clinical trials; standardized Ze 440 extract used in multiple RCTs |
| Liquid | 40 mg | Daily | PMS symptoms including mood, breast tenderness, and bloating | Based on RCTs using liquid extract formulations |
| Tablet | 3.5–4.5 mg | Daily | Fertility support and cycle irregularity | Traditional use supported by observational studies and smaller clinical trials |