Research suggests that the direct evidence linking calcium supplementation to cancer risk reduction is limited within the studies provided, with calcium appearing primarily as a nutritional consideration in adjacent contexts rather than as a focal intervention. The most relevant mention comes from a 2026 narrative review on obesity and cancer, which noted that bariatric surgery patients frequently develop calcium deficiencies that could independently influence cancer risk if left unmanaged, implying a supportive rather than preventive role for adequate calcium status. Several other reviews touching on prostate and breast cancer risk examined a range of dietary and nutritional factors but did not identify calcium as a standout protective agent, and the broader literature represented here skews heavily toward mechanistic and observational work rather than randomized controlled trials specifically testing calcium for cancer prevention. Overall, the available studies provided do not offer a clear or consistent evidentiary basis for concluding that calcium meaningfully reduces cancer risk, and readers interested in this question would be better served by consulting meta-analyses and clinical trials designed specifically to test that relationship.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Obesity, Bariatric Surgery, and Cancer Risk: Nutritional Perspectives and Lon... | Review | 2026 | Mixed | 100 |
| Nutrition, dietary supplements and adenocarcinoma of the prostate. | Review | 2011 | Neutral | 95 |
| Nutritional aspects of primary prostate cancer prevention. | Review | 2011 | Neutral | 90 |
| Spatiotemporal organisation of residual disease in mouse and human BRCA1-defi... | Other | 2025 | Neutral | 85 |
| Chemoprevention of breast cancer: implications for postmenopausal women. | Review | 2002 | Neutral | 85 |
| T-World: A highly general computational model of a human ventricular myocyte | Other | 2025 | Neutral | 80 |
| Self-supervised AI reveals a lethal discohesive phenotype in lung adenocarcinoma | Other | 2025 | Neutral | 75 |
| Cell crowding activates pro-invasive mechanotransduction pathway in high-grad... | Other | 2024 | Neutral | 70 |
| Distinct matrix viscoelasticity in bone fracture hematoma steers macrophage p... | Other | 2025 | Neutral | 65 |
| Connectivity Map and perturbation-based sensitivity analysis identifies MEK i... | Other | 2024 | Neutral | 60 |
| Platelet mitochondrial transfer via extracellular vesicles modulates neutroph... | Other | 2025 | Neutral | 55 |
| Age-dependent tumor-immune interactions underlie immunotherapy response in pe... | Other | 2025 | Neutral | 50 |
| Clinical and molecular characterisation of primary refractoriness to atezoliz... | Other | 2025 | Neutral | 45 |
| Comparative ASCL1 interactome analysis reveals CDK2-Cyclin A2 as suppressors ... | Other | 2025 | Neutral | 40 |
| The selective amyloid-driven failure of cholinergic medial septal neurons in ... | Other | 2025 | Neutral | 35 |
| WS6 enables scalable <i>ex vivo</i> expansion and gene editing of human basal... | Other | 2025 | Neutral | 30 |
| Targeting non-canonical NF-κB signalling in CYLD cutaneous syndrome by select... | Other | 2025 | Neutral | 25 |
| Optimised dissociation and multimodal profiling of prostate cancer stroma rev... | Other | 2025 | Neutral | 20 |
| Pathogenic Keratinocyte States and Fibroblast Niches Define the Tissue Microe... | Other | 2025 | Neutral | 15 |