Research suggests that sulforaphane, a bioactive compound concentrated in broccoli sprouts, may have activity against coronavirus strains, based on preclinical laboratory and animal studies. The available evidence comes from cell culture experiments and mouse models rather than human clinical trials, which represents a significant limitation in drawing firm conclusions about effects in people. Studies indicate that in these preclinical settings, sulforaphane reduced viral replication, lessened lung inflammation, and appeared to work synergistically with an existing antiviral drug, pointing to a potentially interesting avenue for further investigation. However, because no human trials have yet established these findings in people, the current evidence base remains preliminary and should be interpreted with caution.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Sulforaphane exhibits in vitro and in vivo antiviral activity against pandemi... | Other | 2021 | Supports | 85 |