Vitamin B7 (Biotin) for Skin Health

Research suggests that biotin may contribute to skin health, though the available evidence is limited by the fact that biotin has rarely been studied in isolation. The most directly relevant human study is a randomized controlled trial finding that a multi-ingredient supplement containing biotin alongside collagen peptides, vitamins C and E, zinc, and acerola extract improved objective measures of skin hydration, elasticity, roughness, and density over 12 weeks, but because multiple active compounds were present, no conclusions can be drawn about biotin's specific contribution. A 2023 narrative review of nutritional compounds noted promising signals for biotin in skin health, including potential relevance to inflammatory skin conditions, while acknowledging that no consensus exists on optimal use and that further research is needed. The remaining studies in this evidence set examined skin microbiome aging, a canine atopic dermatitis supplement trial, and a laboratory psoriasis model, none of which isolate biotin's effects in humans, leaving the overall evidence base modest and largely indirect.