Berries (General) for Anti-Inflammatory

Moderate evidence 16 studies

Research suggests that berries and berry-derived compounds — including anthocyanins, quercetin, pelargonidin, and other polyphenols — demonstrate meaningful anti-inflammatory properties across a range of laboratory, animal, and review-level studies, with evidence spanning blackcurrants, lingonberries, strawberries, and several lesser-known species such as Brazilian native Eugenia fruits and Campomanesia adamantium. Studies indicate these compounds may work through multiple pathways, including scavenging free radicals, reducing pro-inflammatory signaling molecules like TNF-α and NF-κB, and modulating immune cell activity, with supporting evidence from animal models, cell studies, and numerous narrative reviews. The body of literature is largely preclinical and observational in nature, with the available randomized controlled trial touching only indirectly on berry-related anti-inflammatory effects, and at least one study examining dietary inflammatory patterns found no statistically significant link to a common inflammation marker in a general adult population. Overall, while the convergent direction of the evidence is encouraging, most researchers across these studies emphasize that well-designed human clinical trials are still needed before firm conclusions can be drawn about the magnitude or consistency of berries' anti-inflammatory effects in people.

Related studies

Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.

Title Type Year Direction Match
In Pursuit of Healthy Aging: Effects of Nutrition on Brain Function. Review 2021 Supports 100
Antioxidant and Anti-Inflammatory Effects of Carotenoids in Mood Disorders: A... Review 2023 Supports 95
Pro-inflammatory and anti-inflammatory T cells in giant cell arteritis. Review 2017 Neutral 90
Discovery of a AhR flavonoid agonist that counter-regulates ACE2 expression i... Other 2021 Supports 85
Lingonberries-General and Oral Effects on the Microbiome and Inflammation. Review 2021 Supports 85
Antioxidant and Anti-Inflammatory Activities of Unexplored Brazilian Native F... Other 2016 Supports 80
The power of berries against cardiovascular diseases. Review 2024 Supports 75
Immunostimulatory and anti-inflammatory impact of Fragaria ananassa methanol ... Other 2023 Supports 70
Neuroprotective effects of citrus flavonoids. Review 2012 Neutral 65
Toxicological analysis and antihyperalgesic, antidepressant, and anti-inflamm... Other 2017 Supports 60
Potential Implications of Quercetin and its Derivatives in Cardioprotection. Review 2020 Supports 55
A Dietary Inflammatory Index and associations with C-reactive protein in a ge... Other 2021 Neutral 50
The health benefits of blackcurrants. Review 2012 Supports 45
Flavonoid intake and bone health. Review 2012 Supports 40
Effects of 12 Weeks of Chromium, Phyllanthus emblica Fruit Extract, and Shila... RCT 2025 Neutral 35
Asthma and dietary intake: an overview of systematic reviews. Review 2016 30

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Medical Disclaimer: Noyemi provides information from published research for educational purposes only. This content is not medical advice and does not replace consultation with a qualified healthcare provider. Always consult your doctor before starting, stopping, or changing any supplement regimen, especially if you take medications or have existing health conditions.