Research suggests that baicalein may have anxiety-reducing properties, based on preclinical animal studies. A 2022 study using zebrafish models of acute and chronic stress found that baicalein treatment reversed stress-induced anxiety-like behaviors as measured by standard behavioral tests, indicating a potential anti-anxiety effect. However, the current evidence base is limited to a single animal study, and it is important to note that findings in zebrafish do not necessarily translate to humans. Controlled clinical trials in humans would be needed before any conclusions about efficacy or safety in people could be drawn.
Citations from PubMed and preprint sources. Match score (0-100) reflects automated search ranking, not clinical appraisal.
| Title | Type | Year | Direction | Match |
|---|---|---|---|---|
| Baicalein prevents stress-induced anxiety behaviors in zebrafish model. | Other | 2022 | Supports | 97 |