Artichoke extract, derived from the leaves of Cynara scolymus, has a long history in traditional European herbal medicine and has attracted growing scientific interest in recent decades. Research suggests it may support digestive health by promoting bile production, which can help ease symptoms like bloating, nausea, and discomfort, particularly in individuals experiencing functional dyspepsia or irritable bowel syndrome. Studies indicate that its bioactive compounds, especially cynarin and luteolin, may contribute to healthy cholesterol levels by influencing lipid metabolism, and preliminary evidence points to potential benefits for liver function and blood sugar regulation. While the overall body of research is encouraging, many studies remain small in scale, and further investigation is needed to fully understand the extent of its effects across these areas.
Compare this supplementResearch suggests that artichoke extract may offer modest benefits for cholesterol management, with multiple randomiz...
View studies →Research suggests that artichoke leaf extract may support liver health through several mechanisms, including antioxid...
View studies →Research suggests that artichoke extract and related compounds from Jerusalem artichoke may support blood sugar regul...
View studies →Research suggests that artichoke extract contains a range of potentially beneficial compounds — including chlorogenic...
View studies →The available linked study does not contain research on artichoke extract or digestive health, and instead examines C...
View studies →The available linked study does not contain research on artichoke extract or IBS, and instead examines COVID-19 infec...
View studies →These are commonly referenced dosage ranges for this supplement. They are not medical recommendations. Always consult a healthcare provider before supplementing.
| Form | Dose range | Frequency | Studied for | Source |
|---|---|---|---|---|
| Extract | 1,800 mg | Daily | Alcohol recovery and oxidative stress reduction | Referenced in studies on antioxidant and hepatoprotective activity during alcohol-related liver stress |
| Extract | 300–600 mg | Twice daily | Blood sugar regulation | Used in studies examining glycemic and insulin response, including Nazni et al. |
| Extract | 1,280–1,920 mg | Daily | Cholesterol management | Used in RCTs on lipid-lowering effects, including Bundy et al. and Englisch et al. |
| Extract | 320–640 mg | Three times daily | Digestive health and IBS relief | Common in clinical trials including Walker et al. and Holtmann et al. RCTs on functional dyspepsia and IBS |
| Extract | 600–1,800 mg | Daily | Liver health and bile flow support | Based on clinical trials examining hepatoprotective and choleretic effects |