Andrographis (Expanded) for Fever Management

Research suggests that Andrographis may have some relevance to fever management in the context of infectious illness, though the available evidence linking it specifically to this application in the COVID-19 literature is indirect and preliminary. The single study informing this entry is a 2021 narrative review that surveyed medicinal plants broadly for potential COVID-19 applications, identifying fever relief as one area of interest, but Andrographis was considered alongside many other botanicals rather than as a standalone focus. Studies indicate that the overall body of evidence in this space is largely preclinical or theoretical, and the review's authors explicitly cautioned that clinical trials are needed before firm conclusions can be drawn. The directional signal from this literature is neutral, meaning researchers see enough plausibility to warrant further investigation but have not established that Andrographis reliably reduces fever in human populations.