L-Tryptophan & SAMe (S-Adenosyl Methionine)

Warning Stacking
L-Tryptophan → SAMe (S-Adenosyl Methionine) →
Warning Stacking

Both increase serotonergic activity and combining them may elevate serotonin excessively.

Mechanism

SAMe enhances serotonin turnover. L-Tryptophan is the dietary precursor to serotonin.

Recommendation

Use only one at a time. Do not combine with SSRIs or other serotonergic agents.

Sources

  • Natural Medicines Database
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